The rabies virus is a neutron-tropic type of virus that is likely to cause the disease of rabies in the humans and the animals. The transmission of the rabies virus can take place either through the bite of an animal with virus in it or by the saliva of the animal or even through the contact with the human saliva infected from the virus. The virus of rabies is the species of the rhabidoviridae family and the lyssavirus genus.
What is the Structure of Rabies Virus
The virus of rabies are found enveloped and have a negatively sensed single standard ribo neuclic acid genome. The genetic information of this virus is found as a ribo-nucleo-protein complex package in which the ribo-nucleic-acid is bound tightly by the nucleo -protein that are viral in nature. All the sorts of events of the transcriptions and the replications happen in a virus factory specialized for it only.
Structure of the virus of rabies:-
the virus of rabies is somewhat like a bullet of a gun in shape and have a measurement of about one hundred eighty nanometers and the diameter of the cross sectional area about seventy five nano-meters with one end being a rounded or conical one and other end being concave or planar. The structure of the lyssa virus is of a helical symmetry and thus the infectious particles are cylindrical in the shape.
The viruses of lyssavirus genus are characterized by the broad host spectrum ranging from the insects to the plants and even mammals like elephants. The viruses that infect the humans have a cubical symmetry and that take the shape approximately of a regular polyhedra.
How the infection takes place:-
from the wound or the entry, the virus of rabies makes its way fastly along the neural pathways of the peripheral nervous system in the infected animal and the retrograde axonal transportation of the virus of rabies to the central nervous system is the only step of pathogenesis during the infection of virus.
After reaching the central nervous system, the virus thus makes its way to other organs and the salivary glands that are situated in the tissues of the mouth of the infected being along with the cheeks get high concentrations of the virus and allow it to be transmitted further because of a projectile salivation.
The case of rabies can get fatal ranging from two days to five years from the time of initial infection that largely depends on the species of the animal that acts as the reservoir and most of the infected mammals (animals with mammary glands in them) are likely to die because of it in weeks.